KIMA CHEMICAL CO.,LTD.
KIMA CHEMICAL CO.,LTD.
HPMC K15M

HPMC K15M

KimaCell®HPMC K15M is used as film coating and binder in pharmaceutical tablets, it can significantly improve the solubility of drugs and enhance the water resistance of tablets. It can also be used as suspension, ophthalmic preparation, sustained and controlled release agent matrix and floating tablet, etc. When HPMC K15M is combined with other synthetic polymers and colloidal drugs to prevent water and ethanol from separating from the transparent hydrocolloid and improve water retention, it is also used as a thickener, emulsifier and rheological properties. And other daily chemical industries, etc.


Where to buy Cas 9004-65-3
HPMC K15M

Specification of HPMC K15M


HPMC K15M ( 9004 65 3 )

Hydroxypropyl Methyl Cellulose (HPMC)

Physical Analysis

Appearance

White to slightly off-white fibrous or granular powder.

Identification A to E

Conform

Solution appearance

Conform

Methoxy

19.0-24.0%

Hydroxypropoxy

4.0-12.0%

Loss on drying

5.0% Max

Residue on ignition

1.5% Max

pH

5.0-8.0

Apparent viscosity

12000.0-18000.0cps

Particle size

Min. 98% pass through 100 mesh

Heavy Metals

Heavy Metal

≤10ppm

Arsenic

≤3ppm

Lead

≤3ppm

Mercury

≤1ppm

Cadmium

≤1ppm

Micro bacteria

Total plate count

≤1000cfu/g

Yeast and Mould

≤100cfu/g

Coli form

Absent/g

Salmonella

Absent/g


Application of HPMC K15M


KimaCell® HPMC K15M is widely used in injectable hydrogel. Injectable hydrogel is a type of hydrogel that can exist in a liquid state and be transported to the injection site, respond to certain stimuli such as temperature, ionic strength, etc., and can quickly complete the liquid-solid phase transition. Compared with traditional hydrogels, injectable hydrogels can maintain a liquid state in vitro after being loaded with drugs, and rapidly undergo a phase transition after entering the body, so that the drugs can be released continuously, improve the utilization rate of the drugs, and reduce the occurrence of side effects, achieving more good therapeutic effect. In situ gel is also a part of injectable gel. The unique solution-gel transition properties of in situ gel make it have the advantages of good tissue compatibility, long residence time, high local drug concentration and high bioavailability. HPMC is used as the matrix of some injectable in situ gels, which can be used for the treatment of some diseases that require high drug concentration and drug duration. HPMC K15M is widely used in skin, eyes, mouth, nasal cavity, vagina, rectum, etc. way of administration.


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HPMC K15M