HPMC K15M

Specification of HPMC K15M

Application of HPMC K15M

KimaCell^® HPMC K15M is widely used in injectable hydrogel. Injectable hydrogel is a type of hydrogel that can exist in a liquid state and be transported to the injection site, respond to certain stimuli such as temperature, ionic strength, etc., and can quickly complete the liquid-solid phase transition. Compared with traditional hydrogels, injectable hydrogels can maintain a liquid state in vitro after being loaded with drugs, and rapidly undergo a phase transition after entering the body, so that the drugs can be released continuously, improve the utilization rate of the drugs, and reduce the occurrence of side effects, achieving more good therapeutic effect. In situ gel is also a part of injectable gel. The unique solution-gel transition properties of in situ gel make it have the advantages of good tissue compatibility, long residence time, high local drug concentration and high bioavailability. HPMC is used as the matrix of some injectable in situ gels, which can be used for the treatment of some diseases that require high drug concentration and drug duration. It is widely used in skin, eyes, mouth, nasal cavity, vagina, rectum, etc. way of administration.