KIMA CHEMICAL CO.,LTD.
KIMA CHEMICAL CO.,LTD.
HPMC E50

HPMC E50

KimaCell®HPMC E50 Hydroxypropylmethylcellulose is a multi-purpose non-ionic cellulose derivative, mainly used as a solid preparation disintegration and binder, because its powder has a large surface area and porosity, it can quickly absorb water and swell, and is used in tablets At the same time, the tablet disintegrates quickly, and its rough structure has a large inlay between the drug and the particles, which can significantly increase the hardness of the tablet without affecting the disintegration, thereby accelerating the dissolution rate of the drug and improving the bioavailability. The dosage of this product is generally about 2-5%. In tablet production, it can be used for internal addition in wet granulation, or it can be added externally or both internally and externally for better effect.


Where to buy Cas 9004-65-3
HPMC E50

Specification of HPMC E50


HPMC E50

Hydroxypropyl Methyl Cellulose (HPMC)

Physical Analysis

Appearance

White to slightly off-white fibrous or granular powder.

Identification A to E

Conform

Solution appearance

Conform

Methoxy

28.0-30.0%

Hydroxypropoxy

7.0-12.0%

Loss on drying

5.0% Max

Residue on ignition

1.5% Max

pH

5.0-8.0

Apparent viscosity

40-60cps

Particle size

Min. 98% pass through 100 mesh

Heavy Metals

Heavy Metal

≤10ppm

Arsenic

≤3ppm

Lead

≤3ppm

Mercury

≤1ppm

Cadmium

≤1ppm

Micro bacteria

Total plate count

≤1000cfu/g

Yeast and Mould

≤100cfu/g

Coli form

Absent/g

Salmonella

Absent/g


Application of HPMC E50


KimaCell® HPMC E50 is a chemically inert substance, compatible with most active drugs and preparation excipients. It has following advantages in pharmaceutical excipients:

  • Reduce the difficulty and time of prescription screening

  • Increase the success rate of R&D and accelerate the launch of products

  • Meet the sustained release requirements of various solubility active drugs

  • very narrow viscosity range

  • Ensure the stability of drug release

  • Reduce batch-to-batch variation

  • Strict particle size control - 75μm (200 mesh)

  • Uniform particle size is conducive to the application of powder direct compression process, which is conducive to rapid hydration and gel layer formation

  • Reduce shipping time

  • Guaranteed timely supply

  • Meet the requirements of USP/EP/JP

  • Reduce the number of prescriptions

  • Shorten development time

  • Market acceptability

  • Prescriptions can be considered GMO/TSE/BSE free


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lf you have any questions about our cellulose ether products, please contact us.
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HPMC E50