KimaCell®MC A100 Methylcellulose is a cellulose methyl ether. White or light yellow or light gray small particles, filaments or powder. It is odorless and tasteless, and about 27%~32% of the hydroxyl groups exist in the form of methoxy groups. Different grades of methylcellulose have different degrees of polymerization, ranging from 50 to 1,000; while their molecular weight (average number) ranges from 10,000 to 220,000, and their degree of substitution is defined as the average number of methoxy groups, methoxy The radical is attached to each anhydroglucose unit in the chain.
Methyl Cellulose (MC)
White to slightly off-white fibrous or granular powder.
Identification A to E
Loss on drying
Residue on ignition
5.0 - 8.0
Apparent viscosity, 2% solu, 20℃
Min. 98% pass through 100 mesh
Total plate count
Yeast and Mould
KimaCell® MC A100 Methyl cellulose can increase the viscosity of tears, so that tears stay in the eye for a longer time. It is suitable for dry eyes with excessive evaporation, such as eyelid closure insufficiency, eyelid defect, and insufficient tear secretion; sodium hyaluronate has better water retention. It can increase the stability of the tear film, and can supplement tears and relieve dry eyes for various types and degrees of dry eye; polyethylene is isotonic with natural tears, has good water retention characteristics, and will not It causes blurred vision, but its viscosity is low, and it stays on the ocular surface for a short time, so frequent eye drops are required to maintain the effect. All kinds of artificial tears are used as an ophthalmic solution in contact with the eyes, and the requirements are very strict. They must meet the main component indicators of human tears and must also remove polluting microorganisms.
Real artificial tears should meet the following aspects: 1. Imitate the basic components of human cells; 2. Maintain the functions of human cells; 3. Non-toxic and harmless to the eyes; 4. Longer maintenance time. At present, there are many types and dosage forms of artificial tears, including more than 50 kinds such as aqueous solution, oil solution, gel and eye ointment.
Lubricating and moisturizing type: including methyl cellulose, sodium hyaluronate, polyethylene, etc.