KimaCell®HPMC K100 LV Hydroxypropyl methyl cellulose is white or milky white, odorless and tasteless, fibrous powder or granules, with a drying weight loss of no more than 10%, soluble in cold water but not in hot water, and slowly expands and peptizes in hot water to form a viscous colloidal solution, cooled to a solution, correspondingly to a gel when heated. HPMC has excellent water solubility in cold water. It can be dissolved into a transparent solution in cold water with a little stirring. On the contrary, it is basically insoluble in hot water above 60°C and can only swell. It is a non-ionic cellulose ether. Its solution has no ionic charge, does not interact with metal salts or ionic organic compounds, and does not react with other raw and auxiliary materials in the production process of preparations; it has strong anti-allergic properties, and with the increase of the degree of substitution in the molecular structure, its It is more resistant to allergies and more stable.
HPMC K100 LV ( 9004 65 3 )
Hydroxypropyl Methyl Cellulose (HPMC)
White to slightly off-white fibrous or granular powder.
Identification A to E
Loss on drying
Residue on ignition
Min. 98% pass through 100 mesh
Total plate count
Yeast and Mould
KimaCell® HPMC K100 LV is metabolically inert, and as a pharmaceutical excipient, it will not be metabolized or absorbed, so it does not provide calories in medicines and foods, and has unique applicability to low-calorie, salt-free, non-allergenic drugs and foods required by diabetic patients; It is relatively stable to acid and alkali, but if the pH value exceeds 2~11 and is affected by higher temperature or stored for a long time, its viscosity will decrease; its aqueous solution can provide surface activity, showing moderate surface tension and interface Tension value; it has effective emulsification in the two-phase system and can be used as an effective stabilizer and protective colloid; its aqueous solution has excellent film-forming properties and is a good coating material for tablets and pills. The film coat formed by it has the advantages of being colorless and tough, and adding glycerin can also improve its plasticity.