KimaCell®HPMC K15 LV Hydroxypropyl methyl cellulose, also known as cellulose hydroxypropyl methyl ether, is prepared from cellulose through etherification, and part of the glucose molecules in the cellulose skeleton are covered with methyl Oxygen and hydroxypropoxyl substitution. HPMC is a semi-synthetic natural organic polymer compound. Based on the research on the existing HPMC synthesis method, the method of nitrogen protection alkalization and step-by-step etherification is used to obtain HPMC with high viscosity. The preparation of HPMC is mainly obtained by reacting a mixed etherifying agent of methyl chloride and propylene oxide with alkali cellulose.
HPMC has a three-dimensional space network structure, has strong mechanical properties and carrying capacity, has a large number of hydroxyl groups in the molecule, can form hydrogen bonds with water, and has good water solubility. At the same time, HPMC is non-toxic, has good biodegradability and biological Compatibility, can be used in multiple directions in the pharmaceutical industry.
HPMC K15 LV
Hydroxypropyl Methyl Cellulose (HPMC)
White to slightly off-white fibrous or granular powder.
Identification A to E
Loss on drying
Residue on ignition
Min. 98% pass through 100 mesh
Total plate count
Yeast and Mould
KimaCell® HPMC K15 LV can be used in Hydrogel drug loading.
Hydrogel is a polymer system that uses water as the dispersion medium, contains a large number of hydrophilic groups and hydrophobic groups, and has a three-dimensional network structure. It can absorb a large amount of water, maintain a certain shape, and can swell in water without dissolving. It is a special soft and wet material. Since the hydrogel has good biocompatibility and is non-toxic, it can be modified according to different needs to make gel products with different functions, so that it can go further on the basis of the original excellent performance, or compound It has new excellent properties, such as degradability, easy-to-regulate physical and chemical properties and structure, etc.
Hydrogel is used as a drug-loading system for clinical treatment of diseases, and it is also divided into many different forms, such as injectable hydrogel, biomucoadhesive hydrogel, hydrogel microspheres, etc. Different dosage forms are used for different diseases. It can greatly increase the utilization rate of drugs, reduce side effects, and improve the cure rate of diseases.