In the field of food safety, HPMC stands for Hydroxypropyl Methylcellulose, also known as Hydroxypropyl Methylcellulose in Chinese. It is a common non-ionic cellulose ether, widely used in the food industry, and an internationally recognized food additive.
Hydroxypropyl Methylcellulose is a semi-synthetic polysaccharide derivative derived from natural high-molecular-weight cellulose through chemical modification. It exhibits excellent thickening, film-forming, water-retention, suspension, and emulsion stability properties. HPMC's application in food primarily utilizes its physical properties. Since it is not digested or absorbed by the human body, it is classified as a dietary fiber.
In food, HPMC is classified as a food additive thickener, with the internationally recognized code E464. Its legal use and dosage vary slightly across countries and regions, but it is generally considered a safe, non-toxic, non-allergenic, and non-carcinogenic food additive.
Major regulatory agencies have evaluated its safety as follows:
China: HPMC is permitted for use in certain foods under the "National Food Safety Standard - Food Additives Usage Standard" (GB 2760).
EU: It is permitted as E464 in a variety of foods as a stabilizer or thickener.
US: It is classified as a GRAS (Generally Recognized As Safe) substance by the FDA.
FAO/WHO: The Joint Expert Committee on Food Additives (JECFA) has evaluated it and deemed it safe within reasonable usage limits.
Thickener: Commonly used in beverages, jellies, sauces, etc., to enhance taste and texture.
Emulsion Stabilizer: Used to improve emulsion stability in emulsified foods such as plant-based milks and ice cream.
Film-Forming Agent: HPMC forms a transparent film on food surfaces, used to protect fruits, vegetables, candies, and other products from moisture. Capsule Materials: In vegetarian capsules, HPMC is used as a plant-derived shell material, replacing gelatin. It is heat-resistant and easily soluble.
Low-calorie Foods: As a non-nutritive dietary fiber additive, it is often used in weight-loss foods.
HPMC does not break down in the digestive tract, does not generate heat, is not fermented by microorganisms, does not cause allergic reactions, and is non-toxic to humans. Its use as a functional food additive has been validated through multiple toxicology studies and has shown no significant toxic side effects. At typical dietary doses, HPMC poses no health risks.
However, as a large cellulose molecule, high doses may cause mild bloating or gastrointestinal discomfort. Moderation is recommended, especially for infants, the elderly, or those with weakened gastrointestinal function.
HPMC (hydroxypropyl methylcellulose) is a widely recognized safe additive under food safety standards and has numerous practical uses in the food industry. Its excellent stability, biocompatibility, and functionality make it a preferred alternative to animal-based gums, thickeners, or functional dietary fibers. HPMC is a food excipient that is harmless to the human body and has a wide range of uses, provided that its use and dosage are within compliance.